Out of the primary 1.9 million doses of Pfizer’s COVID-19 vaccine administered in the US, there have been 21 reported circumstances of extreme allergic reactions to the vaccine, the Facilities for Illness Management and Prevention mentioned January 6.
The speed of anaphylaxis seen up to now — 11.1 circumstances per 1 million vaccine doses — is increased than for the flu vaccine, which is 1.three circumstances per 1 million doses, Nancy Messonnier, director of the CDC’s Nationwide Heart for Immunization and Respiratory Illnesses, mentioned in a Jan. 6 information briefing. However the reactions to COVID-19 vaccines are “nonetheless exceedingly uncommon,” she mentioned.
“These are protected and efficient vaccines. We now have good information to indicate that,” Messonnier mentioned. The nation’s surveillance programs for vaccine uncomfortable side effects are “extremely strong,” she mentioned, and “the one factor that we which have seen is these extreme allergic reactions.”
Nonetheless, websites that administer COVID-19 vaccines want to have the ability to acknowledge the indicators of anaphylaxis — which, if it happens, would probably occur shortly after vaccination — and be ready to deal with it, CDC officers mentioned. And individuals who have a historical past of anaphylaxis because of this any trigger ought to be noticed for 30 minutes after receiving a COVID-19 vaccine.
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Anaphylaxis, which could be life-threatening, requires emergency therapy with epinephrine. The UK, which started immunizing its inhabitants towards COVID-19 with the Pfizer vaccine December 8, was the primary nation to report circumstances of the extreme allergic response following vaccinations (SN: 12/11/20).
The CDC reported on the 21 circumstances in the US, which cowl vaccinations given from December 14 to 23, in a Morbidity and Mortality Weekly Report examine printed on-line January 6. These first vaccinations had been solely with Pfizer’s vaccine. Officers don’t but know what’s inflicting the allergic response after immunization with the vaccine.
There have been no deaths from anaphylaxis reported within the examine. Nineteen of the 21 folks had been handled with epinephrine and 4 had been hospitalized. Seven of the folks within the report had skilled anaphylaxis prior to now. CDC officers advocate that folks with a historical past of anaphylaxis alert the particular person administering the shot earlier than getting it.
The CDC is continuous to watch for these reactions. Because the report’s information had been analyzed, the entire variety of reported reactions in the US has grown barely to 29 circumstances. A few of these had been tied to vaccination with the Moderna COVID-19 vaccine, the company mentioned on the information briefing.